Biosphere 2 was a giant sealed world. Eight humans were locked in with a mass of flora and other fauna, and a balanced ecosystem was supposed to naturally emerge. But from the start it was completely unbalanced. The CO2 levels started soaring, so the experimenters desperately planted more green plants, but the CO2 continued to rise, then dissolved in the "ocean" and ate their precious coral reef. Millions of tiny mites attacked the vegetables and there was less and less food to eat. The men lost 18% of their body weight. Then millions of cockroaches took over. The moment the lights were turned out in the kitchen, hordes of roaches covered every surface. And it got worse – the oxygen in the world started to disappear and no one knew where it was going. The "bionauts" began to suffocate. And they began to hate one another – furious rows erupted that often ended with them spitting in one another's faces. A psychiatrist was brought in to see if they had gone insane, but concluded simply that it was a struggle for power.-- from Adam Curtis on How the 'ecosystem' myth has been used for sinister means
Then millions of ants appeared from nowhere and waged war on the cockroaches. In 1993 the experiment collapsed in chaos and hatred.