Turning from policy to science, RealClimate has a useful post, The certainty of uncertainty, commenting on Gerard Roe and Marcia Baker's Why is climate sensitivity so unpredictable?. For example:
450 ppm is an oft-cited threshold since this keeps deltaT below 2°C using standard climate sensitivities. But the skewed nature of the distribution of possible sensitivities means that it is much more likely that 450 ppm will give us more than 4.5°C of global warming rather than less than 2°.
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